Download E-books Antitumor Steroids PDF

Antitumor Steroids examines using steroids, besides nonsteroidal antiestrogens and a few benzo[a]carbazoles, within the remedy of melanoma. It explains the mechanism during which steroids and their receptors interact to impact their physiological features mostly and their antitumor job particularly. It additionally describes the systematic screening of antitumor compounds remoted from average resources.
Organized into 9 chapters, this e-book starts with an outline of the position of steroids in melanoma therapy. It then discusses the estrogens, antiestrogens, and compounds (all containing an fragrant A-ring). the following chapters think of androgens, a few antiandrogens, derivatives in accordance with C-19 steroids, progestins and corticoids, bile acids, and compounds with a side-chain carboxyl crew. The ebook explains the biogenesis and metabolism of androgens; the pharmacology of medroxyprogesterone acetate; the antitumor homes of certainly happening corticosteroids; sterols and cucurbitacins; diet D and its metabolites; and cardenolides, bufadienolides, and withanolides. The publication concludes with a bankruptcy on bile acids, sapogenins and its analogs, and miscellaneous steroids.
This e-book is a useful source for natural and medicinal chemists biochemists, and pharmacologists attracted to using steroids in treating melanoma.

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